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Evaluating measurement uncertainty in clinical chemistry – Case studies
This report describes the ‘top-down’ approach to the evaluation of measurement uncertainty in the context of clinical chemistry. The ‘top-down’ approach makes use of information on the performance of whole measurement procedures, such as data obtained from routine internal quality control and external quality assessment. The strengths and weaknesses of the data commonly available to laboratories for uncertainty evaluation are discussed. The approach is illustrated by considering measurement procedures for the determination of creatinine in serum and catecholamines in urine.
- Author - Barwick V
- Reference Number - LGC/R/2010/17
Last modified on
25 April 2012.