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Silver nanoparticle enhanced silver ion stress response in Escherichia coli K12
This study investigated the dissolution-based toxicity mechanism for silver nanoparticles to Escherichia coli K12. The silver nanoparticles, synthesised in the vapour phase, are effective anti-bacterial agents against the Gram-negative bacterium, E. coli K12. The nanoparticles associate with the bacterial cell wall, appearing to interact with the outer and inner membranes, and then dissolve to release Ag+ into the cell and affect a transcriptional response. The dissolution of these nanoparticles in a modified LB medium was measured by inductively coupled plasma mass spectrometry (ICP-MS) and has been shown to follow a simple first-order dissolution process proportional to the decreasing surface area of the nanoparticles.
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- Author - McQuillan J,Goenaga-Infante H, Stokes E, Shaw A
- Reference Number - doi:10.3109/17435390.2011.626532
Last modified on
06 February 2012.