Key Topics

Studies of past programme outputs in the field of mass spectrometry

Showing 1 to 6 of 6 articles.

About these case studies

Significant technical developments in mass spectrometry (MS) over almost 20 years since the first VAM programme have led to a marked increase in its importance to analytical science.

Characterisation of a food CRM for iodine using radioactive I as the spike for a novel IDMS technique

Iodine’s primary function in the body is in the formation of vital thyroid hormones, required for the maintenance of metabolic rate, cellular metabolism and integrity of connective tissue.

IDMS certification of clinical reference materials using LC-MS/MS

Currently routine methods measuring the concentrations of some drugs, hormones and peptides in body fluids are largely based on immunoassay and spectroscopic/enzymatic techniques. However it has been well documented that these routine methods can generate invalid data due to interference/cross reactivity and bias.

Authenticity of pharmaceuticals using organic and inorganic natural isotope ratios

LGC has been involved for many years in the use of mass spectrometry methods for the measurement of isotope ratio amounts using IRMS

Characterisation of organic compounds using accurate mass measurements and product ion spectra

The two main types of mass spectrometry measurements used to characterise molecules have been the focus of a number of VAM projects and are described in this article.

Identification of key dietary selenium compounds important to health

Knowledge of the selenium compounds (species) in food supplements during production and consequent digestion, absorption and utilisation by the body is essential.

Showing 1 to 6 of 6 articles.